| ALMAGEST | A work on astronomy, compiled by Ptolemy in the 2nd century AD, containing a description of the geocentric system of the universe and a star catalogue |
| GRAMMAR | The morphology and syntax of a language; a book containing a description of said linguistry; or, the basic rules of a field of knowledge (7) |
| SAGITTA | From the Latin meaning "arrow" and listed by Ptolemy in the 2nd century, one of the constellations i |
| TIVOLI | Hadrian's Villa, built in the 2nd century CE at this Italian city, is considered the epitome in architecture of the opulence and elegance of the Roman world. The villa, also known as Villa Adriana, wa |
| IGNATIUS | St ___ of Antioch, theologian and Bishop of that city martyred in the second century AD (8) |
| APULEIUS | Roman writer of the 2nd century AD best known for the picaresque novel Metamorphoses or The Golden Ass (8) |
| PTOLEMY | Influential Greek astronomer and geographer of the 2nd century AD; author of the Almagest and Geography (7) |
| DAPHNISANDCHLOE | The only known work of the 2nd century AD Greek novelist Longus |
| RUNES | Letters comprising the futhork alphabet, used especially in Britain and Scandinavian from around the 2nd century AD (5) |
| CARLVON | and 6dn, Prussian general; author of the unfinished On War, a work on military strategy (4,3,10) |
| TEUTON | A member of an ancient Germanic people from Jutland who migrated to Gaul in the 2nd Century B.C. (6) |
| ROME | First city to reach a population of one million people, in the second century B.C. |
| LUCIAN | 2nd century AD writer of Dialogues of the Dead (6) |
| HASMONEAN | Dynasty of ancient Judea, whose first ruler was Simon Maccabeus in the second century BC (9) |
| REDACTION | Editing a work on origin of Dada movement |
| ETCHERS | Artists in a Works on Paper department |
| ESSENES | Ascetic Jewish sect, originating in the second century BC |
| PIUS | Papal name first used in the second century |
| GALEN | Roman physician born in the second century |
| JUVENAL | Roman poet known for his 2nd century AD collection Satires (7) |
