| NIGHTBLINDNESS | A reason to tread carefully ? in labs, things end badly when extracting last of plasma (5-9) |
| THE | Did this character title have to tread carefully in her position (3,8) |
| DIPLOMAT | Did this character title have to tread carefully in her position (3,8) |
| BADNOTE | It's unpleasant when things end on one |
| MASSIF | Poles extracting last of it provided large amount of rock |
| AERATED | Each little one has to tread carefully when it's charged with gas |
| TOIL | It's hard work extracting last of Brent crude (4) |
| SCAM | Swindle as rascal, extracting last penny (4) |
| MAKE | Prepare starters meticulously, always using knife when extracting core |
| MAIZE | Complicated route when extracting iodine from this crop |
| SALVE | It's soothing when extracting silver from recovered wreck |
| INTHEASCENDANT | Rising in haste, can't end badly (2,3,9) |
| STAR | A luminous sphere of plasma born from the gravitational collapse of a giant molecular cloud (4) |
| CREEP | Tread carefully when it comes to trigger movement (5) |
| WATCHYOURSTEP | "Tread carefully!" ... or a hint to four dangers in this puzzle |
| TRADE | Tread carefully when it comes to commerce (5) |
| SPICULE | A minute needle-like body of crystal, ice or coral/sponge skeleton; or, a jet of plasma ejected from the Sun's chromosphere (7) |
| SHARPLESSON | Does it teach you to handle a knife carefully? (5,6) |
| RATED | Tread carefully when graded (5) |
| ONESSTEP | *Tread carefully, as a matter of course |
