| UPHEAVAL | A large-scale disturbance or disruption (8) |
| UPTURN | A disturbance or disruption; an inverted or topsy-turvy part; a rising trend in fortunes or economic conditions; or, any improvement (6) |
| RIOT | Large-scale disturbance of the peace |
| INCIDENT | Disturbance or din &c. in ground (8) |
| SABOTEUR | One causing deliberate damage or disruption |
| COMMERCE | The interchange of merchandise on a large scale between nations or individuals (8) |
| COLOSSAL | Energy provider accepting failure on a large scale (8) |
| MASSACRE | Slaughter on a large scale (8) |
| INDUSTRY | Lack-lustre stars attempt business activity on a large scale (8) |
| CONCERTI | Musicals on a large scale trick station badly in Channel Islands (8) |
| SYMPHONY | From the Greek meaning "concord/harmony of sound", a large-scale work for an orchestra (8) |
| BIENNALE | A large-scale art show, especially one held every two years (8) |
| ORATORIO | A large-scale, usually narrative musical work for orchestra and voices (8) |
| GENOCIDE | Surprise over denial from police department - it's a killer on a big scale (8) |
| DEMIURGE | Half-formed desire to be a large-scale creator |
| SPENDERS | Big ___ : buyers on a big scale ? (8) |
| SWEEPING | Top of sluice losing liquid on a big scale (8) |
| ENORMOUS | Total runs one piled up including nothing on a big scale |
| NOISE | Word meaning band of musicians, disgust, disturbance or possibly nausea or seasickness originally, now a din, clamour, racket or sound of any kind (5) |
| STIR | A disturbance or mix, whether of one's coffee, emotions or wok-fried supper agitated with chopsticks (4) |