| GILAMONSTER | A large, venomous, brightlycoloured lizard inhabiting deserts of the South Western US and Mexico (4,7) |
| AGAMA | A small terrestrial lizard inhabiting warm regions of the Old World (5) |
| BUTTE | An isolated, steep-sided, flat-topped hill in the western United States and Canada |
| IGUANAS | Tropical lizards inhabiting Antiguan ash-heaps |
| NEWMEXICO | A state of the south-western US, crossed by the Rio Grande and the Pecos River (3,6) |
| GILA | ___ monster, a large, venomous, brightly coloured lizard native to Mexico and the Southwestern US (4) |
| BEDOUIN | A member of any of the nomadic Arab tribes inhabiting the deserts of Arabia, Jordan and Syria, as well as parts of the Sahara (7) |
| CHOLLA | Spiny cactus of the genus Opuntia found in Mexico and the south-western US; from Spanish, 'head' or skull' (6) |
| OCOTILLO | Flowering spiny shrub of Mexico and the south-western US (Fouquieria splendens) known by names including coachwhip, Jacob's staff and vine cactus (8) |
| FENNEC | A very small big-eared nocturnal fox inhabiting deserts of N Africa and Arabia |
| FRIJOL | Generic term for bean, especially in Mexico and the south-western US (6) |
| APACHE | Native American peoples of the south-western US (6) |
| ARIZONA | State of the south-western US (7) |
| PUEBLOS | Towns or villages in Latin America and the south-western US, especially native American settlements (7) |
| MESA | Isolated flat-topped hill with steep sides, especially in the south-western US; Spanish, 'table' (4) |
| NAVAJO | Indigenous people of the south-western USA (6) |
| JOSHUATREE | A small yucca native to the deserts of south-west US (6,4) |
| JOSHUA | The -- tree is a yucca plant of the south-western U.S. (6) |
| SIMOOM | A strong suffocating sand-laden wind of the deserts of Arabia and North Africa |
| IBADAN | Third most populous city of Nigeria; capital of the south-western Oyo State (6) |