| CAVENDISH | A famously eccentric and brilliant British scientist who discovered hydrogen and "weighed the world" - he was a master of gases, gravity, measures and might, yet so shy and reclusive he had an extra h |
| CRICK | Francis ---, British scientist who identified the molecular structure of DNA with James Watson in 1953 (5) |
| SMITHSON | James -, British scientist who left a bequest to found an educational institution in Washington DC (8) |
| COPERNICUS | Polish scientist who discovered that the Earth revolves around the Sun |
| CURIE | Scientist who discovered radium and polonium with her husband (5) |
| RADON | Densest of the seven naturally-occurring chemical elements comprising the noble gases group, discovered by British scientists Robert B. Owens and Ernest Rutherford in 1899 (5) |
| MACAW | A large, tropical parrot with a long tail and brilliant plumage (5) |
| ROOM | The -, a famously bad movie from 2003 which inspired 2017's The Disaster Artist (4) |
| LISTENER | The ---, defunct magazine with a famously complex crossword that now runs in The Times |
| ANCHOR | It is cast and weighed, stopping and starting (6) |
| SETSAIL | Positioned the canvas and weighed anchor (3,4) |
| CPSNOW | British scientist/novelist who lectured on "The Two Cultures" |
| DEBATED | Weighed the pros and cons of |
| FARAD | Unit of electrical capacitance named in honour of a British scientist (1791-1867) |
| OMEGA | Old and brilliant a" the ultimate character! (5) |
| DIOR | Couturier who designed according to a famously wasp-waisted silhouette |
| EIGER | Mountain of the Bernese Alps with a famously challenging north face (5) |
| ULM | German city on the Danube whose minster has a famously high spire (3) |
| AMALFI | Commune in Salerno, the main town on a famously picturesque coast (6) |
| TELLTALEHEART | With "The," 1843 short story with a famously unreliable narrator |
