| TED | 2012 Seth MacFarlane film about a talking bear |
| WAYS | "A Million ___ to Die in the West"; Seth MacFarlane film |
| DIE | "A Million Ways to _ in the West"; Seth MacFarlane film |
| BABE | 1995 film about a talking pig, with Miriam Margolyes (4) |
| PSA | Spot with a talking bear, maybe: Abbr. |
| DAD | Animated Seth MacFarlane comedy about a CIA agent, American --- (3) |
| WAYSTO | Seth Macfarlane comedy, A Million _ Die in the West (4,2) |
| AMERICANDAD | Seth MacFarlane-created animated series about the unconventional Smith family |
| WAYSTODIA | Western comedy with Seth Macfarlane and Charlize Theron, A Million ___ in the West (4,2,3) |
| GUY | "Family ___" (Seth MacFarlane cartoon) |
| ACADEMYAWARDS | Seth Macfarlane hosted these in 2013 |
| BRIAN | "Family Guy" dog voiced by Seth MacFarlane |
| THEORVILLE | Science fiction series that stars "Family Guy" creator Seth MacFarlane |
| FAMILYGUY | Animated sitcom created by Seth MacFarlane (6,3) |
| AMERICAN | Seth MacFarlane animated series, -------- Dad! (8) |
| ORVILLE | Sci-fi series starring Seth MacFarlane (The -------) |
| PETER | Voiced by Seth Macfarlane in Family Guy, ----- Griffin (5) |
| CLEVELAND | The _ Show, grown-up animation from Seth MacFarlane (9) |
| CARLSAGAN | His "Cosmos" series may be rebooted by Seth MacFarlane |
| EMCEE | Seth MacFarlane, at the 2013 Oscars, e.g. |