| TATU | 2000s Russian music duo who teased onstage kisses |
| DONALDTRUMP | Billionaire who teased about running for president in 2000 as the Reform Party candidate |
| DAFTPUNK | French electronic music duo who released the song Get Lucky with vocals by Pharrell Williams in 2013 (4,4) |
| CHASE | ___ & Status, British drum and bass music duo who had a No. 1 hit in 2024 in collaboration with Stormzy (5) |
| SONNYBONO | Member of a 1960s music duo who died in 1998 after hitting a tree while skiing (5,4) |
| GLINKA | The Father of Russian Music |
| NUTCRACKERSUITE | Some Russian music fan, crazy, entirely losing head (10,5) |
| ABBOTTANDCOSTELLO | Comedy duo who created the "Who's On First?" routine |
| DARYLHALL | Half of a famed music duo who both sued and also got a restraining order against 22-Across last week |
| EURYTHMICS | Duo who performed their song "Would I Lie to You?" to open the second MTV Video Music Awards in 1985 |
| CHAS | _ _ _ _ & Dave, British pop rock duo who were pioneers of so-called rockney music (4) |
| JOHNOATES | Other half of the famous duo, who are currently involved in a lawsuit over rights to their music catalog |
| GARFUNKEL | US folk rock duo who were one of the best-selling music acts of the 1960s, Simon & _ (9) |
| ERNIEWISE | British comedy duo who played the music halls back in 1943, Eric Morecambe and ... (5,4) |
| HALLANDOATES | Duo who met in 1967 at Temple University |
| DJJAZZYJEFF | Half the duo who did "I Think I Can Beat Mike Tyson" |
| ERASURE | Synthpop duo who sang "Chains of Love" |
| SHANKS | --- & Bigfoot, duo who had a 1999 hit with Sweet Like Chocolate (6) |
| RAESREMMURD | Duo who featured Nicki Minaj on "Throw Sum Mo": 2 wds. |
| ANTANDDEC | Duo who host BGT (3,3,3) |