| MAINSTREET | 1920 Sinclair Lewis novel set in the town of Gopher Prairie, Minnesota (4,6) |
| MAIN | ___ Street, Sinclair Lewis novel set in Minnesota (4) |
| STREET | 1920 novel by Sinclair Lewis set in Gopher Prairie, Minnesota (4,6) |
| MAINST | Pt. of Gopher Prairie |
| EDEN | ___ Prairie, Minnesota |
| NERVEPINCH | In the town of Vulcan, Alberta there is a replica of the U.S.S. Enterprise ...aboard the actual "Star Trek" starship, crew member Mr. Spock is known for his martial maneuver known as the Vulcan what?: |
| ARROWSMITH | Sinclair Lewis novel for which he received (but declined) the Pulitzer Prize |
| PUPIL | 'The ----- ', Iris Murdoch novel set in the town of Ennistone (12,5) |
| PHILOSOPHERS | 'The ----- ', Iris Murdoch novel set in the town of Ennistone (12,5) |
| BOB | TV animation set in the town of Brixwood, ... the Builder (3) |
| MIKADO | The -, operetta set in the town of Titipu (6) |
| LAST | Foggy milieu of sitcom set in the town of Holmfirth (4,2,3,6,4) |
| WINE | Foggy milieu of sitcom set in the town of Holmfirth (4,2,3,6,4) |
| SUMMER | Foggy milieu of sitcom set in the town of Holmfirth (4,2,3,6,4) |
| OFTHE | Foggy milieu of sitcom set in the town of Holmfirth (4,2,3,6,4) |
| WILSON | 1894 novel by Mark Twain set in the town of Dawson's Landing (9,6) |
| PUDDNHEAD | 1894 novel by Mark Twain set in the town of Dawson's Landing (9,6) |
| THEMIKADO | Gilbert & Sullivan opera set in the town of Titipu (3,6) |
| ZENITH | Presumably this is the highest city in Winnemac, a fictional US state in the Sinclair Lewis novel Ba |
| WEEDS | Showtime show set in the town of Agrestic |