| DONGIOVANNI | 1787 Mozart opera with an Italian libretto by Lorenzo Da Ponte (3,8) |
| LABOHEME | 1896 opera by Giacomo Puccini with an Italian libretto by Luigi Illica and Giuseppe Giacosa (2,6) |
| SUA | "Dalla ___ Pace": Aria in 1787 Mozart opera Don Giovanni |
| COSIFANTUTTE | Italian language opera buffa by Wolfgang Amadeus Mozart whose libretto was written by Lorenzo Da Ponte |
| THEMAGICFLUTE | 1791 Mozart opera with a German libretto by Emanuel Schikaneder (3,5,5) |
| EINEKLEINE | *With 52-Across, 1787 Mozart composition |
| AIDA | Opera with an Ethiopian heroine |
| ILREPASTORE | Mozart opera, K 208, with a libretto by Metastasio |
| IMASNADIERI | 1847 opera by Giuseppe Verdi to a libretto by Andrea Maffei, based on Die Rauber by Friedrich von Schiller |
| BIOMEDICINE | Bone broken by Lorenzo, say, requiring adoption of current stress-related science |
| COSIFAN | One of Mozart's 'da Ponte' operas (4,3,5) |
| RIALTO | Stone-arch bridge in Venice designed by Antonio da Ponte (6) |
| MAGIC | Famous opera by Mozart, with libretto by Emmanuel Schikaneder (3,5,5) |
| THE | Famous opera by Mozart, with libretto by Emmanuel Schikaneder (3,5,5) |
| FLUTE | Famous opera by Mozart, with libretto by Emmanuel Schikaneder (3,5,5) |
| AUFNAXOS | Opera by Richard Strauss with a libretto by Hugo von Hofmannsthal (7,3,5) |
| ARIADNE | Opera by Richard Strauss with a libretto by Hugo von Hofmannsthal (7,3,5) |
| PAGLIACCI | Italian opera with music and libretto by Ruggero Leoncavallo, first performed in 1892 (9) |
| ARABELLA | Lyric comedy by Richard Strauss, his final opera with a libretto by Hugo von Hofmannsthal |
| BRONZE | An alloy of copper and tin used by Lorenzo Ghiberti to make the doors of the Florence Baptistery and also by Andrea del Verrocchio and Donatello in notable equestrian sculptures (6) |