| FRANKENSTEIN | 12's novel outspoken genius needing information in the first instance |
| TWOBYTWO | Women held in roadside robbery in the first instance talk with officers in pairs (3,2,3) |
| PRIMARILY | Wearily dismiss us as formerly precise in the first instance (9) |
| GOALKEEPER | Banks perhaps aim to maintain excellent rates in the first instance (10) |
| BOLDNESS | In the first instance, Biden's age is a striking characteristic |
| NUFF | In the first instance, niceties usually feel fairly sufficient |
| OWNUP | Have untold pride in the first instance and confess (3,2) |
| TRUE | You’re right in the first instance to have regrets |
| SMOCKS | Protection for art students in the first instance sitting practice exams (6) |
| GROT | Rubbish is, in the first instance, going to decay (4) |
| TRICEPS | One extending journeys round continental Europe in the first instance (7) |
| UDOMETERS | What Met man uses elaborately to measure drops in the first instance address depth (9) |
| SHELLEY | Author of one of the first instances of science fiction |
| AGENDA | The girl got the information in the programme (6) |
| GENDARME | Policeman needing information runs in titled lady |
| GENOA | Needing information, ring a city in Italy |
| GREYMATTER | Serving to process information in the brain, one of the types of tissue forming part of the central |
| CLOUDBURST | Information in the sky split open in thunderous affair (10) |
| REFLECTION | Official choosing to ignore first instance of base work of The Mirror? (10) |
| ATTRIBUTION | Close to bone in teaching, ignoring first instance of current assignment |
