| GALL | --- bladder, a muscular, pear-shaped sac that stores bile and ejects it into the duodenum (4) |
| GALLBLADDER | Muscular sac, attached to the right lobe of the liver, that stores bile and ejects it into the duodenum (4,7) |
| CYST | Closed sac that develops abnormally in some body structure (4) |
| SWIM | Gas sac that controls fish's buoyancy (4,7) |
| TILL | Register quavering vocalisation and eject tenor on the right |
| ESPY | Award won by Simone Biles and Serena Williams |
| PYLORUS | Muscular opening in the stomach that regulates the passage of partially digested food (chyme) into the duodenum (7) |
| PERICARDIUM | Membranous sac that surrounds the heart, anchored by ligaments to the central part of the diaphragm and the rear of the sternum (11) |
| APPENDIX | What is the tube-shaped sac at the end of the large intestine? (8) |
| PANCREAS | Large gland behind the stomach that secretes digestive enzymes into the duodenum (8) |
| FOURHUMORS | In medieval physiology, the elemental fluids blood, phlegm, black bile and yellow bile: 2 wds. |
| LIVER | Organ of the body that secretes bile and detoxifies certain poisons (5) |
| DEADEND | A cul-de-sac that leads to the cemetery? (4,3) |
| BURSA | A small, fluid-filled sac that reduces friction between movable parts of the body (5) |
| PUTSABOUT | Turns round and ejects a sailor (4,5) |
| HUMOURS | In early western physiological theory, there were four of these: blood, phlegm, yellow bile and black bile (7) |
| TAURINE | Amino acid found in bile and nerve tissue, named from the Latin for "bull" (7) |
| TURFOUT | Tut! Grab the disorderly four and eject (4,3) |
| SUNISALEE | With Simone Biles and Hezly Rivera, one of the five Golden Girls (gold medal-winning gymnasts of Team USA at the 2024 Paris Olympics): 2 wds. |
| INEDIBLE | Dine at sea, stimulating bile, and any food might seem thus (8) |
