| DROMIO | ? of Ephesus and ? of Syracuse, twin slaves in William Shakespeare play The Comedy of Errors (6) |
| ERRORS | The Comedy Of ____, William Shakespeare play set in the Greek city of Ephesus (6) |
| ADRIANA | Wife of Antipholus of Ephesus in the William Shakespeare play The Comedy of Errors (7) |
| TURKEY | Country containing the ruins of Ephesus and Troy (6) |
| ANTIPHOLUS | Name of twin brothers in William Shakespeare play The Comedy of Errors on whom the twin brothers named Dromio are attendant (10) |
| TEMPLE | Structure built in honor of the Greek goddess Artemis in the ancient city of Ephesus |
| ANGELO | Maker of a fine gold chain in The Comedy of Errors (6) |
| LAIDIN | "They must be bound and ___ some dark room": "The Comedy of Errors" |
| MEXICO | Destination for many runaway slaves in the mid-19th century |
| HELOTS | They worked like slaves in various hotels |
| SYRACUSE | Home city of Egeon, father of the Antipholus twins in Shakespeare's The Comedy of Errors (1594) |
| SPARTACUS | The most notable leader of the slaves in the Third Servile War, a major uprising against the Roman Republic (9) |
| DEPARTS | Wife of Antipholus of Ephesus in 'The Comedy of Errors' (7) |
| IONIA | Site of Ephesus and Colophon |
| ADDLEPATED | "Poor slaves in metre, dull and ____" (Dryden in Absalom and Achitophel) |
| SPIRITUAL | A type of religious song created by African slaves in the American South (9) |
| CERIMON | He was a lord of Ephesus. In Pericles (act 3, scene 2), Second Gentleman of Ephesus says, "Your honor has through Ephesus pour'd forth/ Your charity,... / Your purse, still open, hath built Lord ___." |
| EPHESUS | Setting of Shakespeare's The Comedy of Errors |
| TIMOTHY | Saint and a disciple of Paul; the first Christian bishop of Ephesus (7) |
| EPHESIANS | Paul wrote an epistle to the denizens of the ancient city of Ephesus |