| NOMANISANISLAND | '-- -- -- -- --, entire of it self' (John Donne) (2,3,2,2,6) |
| TAPE | It self-destructs on "Mission: Impossible" |
| DNA | It self-replicates |
| EGOTISTS | Only absorbed in themselves are these. Get it, self-seeking heads so mixed up? (8) |
| DEATHBENOTPROUD | Opening words of John Donne's Sonnet X, by which it is also known (5,2,3,5) |
| NOMAN | "___ ___ is an island entire of itself..." - John Donne |
| ISLAND | "No man is an ..., entire of itself" (John Donne) |
| DONNE | "No man is an island, entire of itself" writer |
| IZAAK | First name of the author of the fishing treatise The Compleat Angler who also wrote a short biography of his friend John Donne (5) |
| DESPAIR | '___ is the damp of hell, as joy is the serenity of heaven': John Donne (7) |
| ANNE | "John Donne, ___ Donne, Undone" |
| STPAULS | London burial place of John Donne and Horatio Nelson |
| FLEA | Biting subject matter of a John Donne poem (4) |
| NOMANIS | Famous aphorism by English poet John Donne, in the 17th devotion, Meditation XVII, of the 1624 prose work Devotions upon Emergent Occasions (2,3,2,2,6) |
| ANISLAND | Famous aphorism by English poet John Donne, in the 17th devotion, Meditation XVII, of the 1624 prose work Devotions upon Emergent Occasions (2,3,2,2,6) |
| THEFLEA | Posthumous John Donne poem that includes "It suck'd me first, and now sucks thee" |
| CHANGE | "___ is the nursery of music, joy, life, and eternity" - John Donne (6) |
| IDIED | "When ___ last...": John Donne |
| BENOT | "Death, ___ proud ...": John Donne |
| ELEGIST | Fifth-rate celebrities, including (for instance) John Donne? (7) |