| THANKSALOT | "Very helpful!," ironically or not |
| ISAAC | Hebrew-derived name meaning "he laughs" which, ironically or funnily enough, was that of the brilliant but serious scientist Newton, alleged to have laughed precisely twice (5) |
| WHATATIME | With 22-Across, "Boy, life sure is exciting right now" (ironically or otherwise) |
| GODSEND | A very helpful or valuable event, person or article (7) |
| ORNO | Of little ___ ___ use (Not exactly helpful!) |
| GOODSAMARITAN | A dragon aims to, changing into a very helpful person |
| BISHOPRIC | See one store kept by person very helpful mostly |
| INSTRUMENTAL | Very helpful, doing without singers |
| COMESUPTRUMPS | Unexpectedly behaves in very helpful way (5,2,6) |
| SHANDY | Starts some very helpful mixed beverage |
| CLUE | Oddly coloured very helpful hint |
| GOA | ___ long way (be very helpful) (2,1) |
| HOTLEAD | Very helpful tip, informally |
| TRUMPS | Cards turned up in a very helpful way (6) |
| THINNER | Container ships missing Picasso? The painter finds it helpful! (7) |
| WHATAPAL | "You're so helpful!" |
| LIFELINE | Figure a cat can be vitally helpful! (8) |
| YOUREALIFESAVER | "That was so incredibly helpful!" |
| OBLIGING | Love soldier wearing flashy jewellery, that's helpful! (8) |
| SERVEWELL | To do so would be very helpful for tennis player (5,4) |
