| ITSASIGN | "The universe is telling us something' |
| DOUGLASADAMS | Sci-fi writer who wrote that the answer to the universe is the number 42 |
| HUBBLESLAW | Key principle behind the theory that the universe is expanding |
| OUTOFTHISWORLD | The rest of the universe is marvellous (3,2,4,5) |
| HUBBLE | Edwin, American astronomer whose work led to the discovery that the universe is expanding (6) |
| REDSHIFT | In astronomy, the displacement of spectral lines towards longer wavelengths, seen as evidence that the universe is expanding (8) |
| ABSURDISM | The philosophical theory that the universe is irrational and meaningless (9) |
| OSMOSIS | The universe is losing carbon by diffusion (7) |
| ONO | Everything in the Universe Is Unfinished author Yoko |
| NASA | Org. that confirmed the universe is expanding |
| PTOLEMY | Astronomer for whom a geocentric model of the universe is named |
| SENSE | "The universe is under no obligation to make _ to you": Neil deGrasse Tyson (5) |
| LAGNIAPPE | In the US, something given as a bonus or gratuity |
| SANCTUS | Hymn originally sung at night can teach us something |
| GREENLIGHT | Briefing, ultimately lengthier, could give us something to go on |
| SUSS | Gives us something to work out in plain view (4) |
| EYEPIECE | Iris, perhaps, gives us something to look into (8) |
| ARC | The ___ of the moral universe is long . . . |
| RELATIVE | It is telling for a member of the family (8) |
| RELATION | It is telling for a member of the family (8) |