| JIMPARSONS | "The Big Bang Theory: star |
| MAYIM | The Big Bang Theory star Bialik |
| CUOCO | "The Big Bang Theory" star Kaley |
| KUNAL | The Big Bang Theory star, ___ Nayyar (5) |
| PARSONS | The Big Bang Theory star, Jim ___ (7) |
| JIM | The Big Bang Theory star, ... Parsons (3) |
| MAYIMBIALIK | Shown, "The Big Bang Theory" star: 2-wds. |
| GALECKI | Johnny _, The Big Bang Theory star (7) |
| JOHNNY | The Big Bang Theory star, _ Galecki (6) |
| YLEM | According to the big bang theory, the hypothetical substance from which the elements developed (4) |
| HOYLE | English astronomer who rejected the "Big Bang" theory of the origins of the universe, d. 2001 (5) |
| JOHNNYGALECKI | Leonard Hofstadter in the TV sitcom The Big Bang Theory and David Healy in the TV sitcom Roseanne are roles played by this US actor, whose films include Hancock and Vanilla Sky (6,7) |
| ATOM | Symbol in the logo of "The Big Bang Theory" |
| GEEKS | The guys in "The Big Bang Theory" |
| WIL | "Star Trek" and "The Big Bang Theory" actor Wheaton |
| LEMAITRE | The priest and astronomer who first proposed the Big Bang theory (8) |
| ARMITAGE | Child actor Iain who plays the title role in "The Big Bang Theory" spin-off "Young Sheldon" |
| PASADENA | California town where the sitcom The Big Bang Theory is set (8) |
| SHELDONCOOPER | "The Big Bang Theory" character with the catchphrase "Bazinga!": 2 wds. |
| DETONATE | Make the Big Bang Theory a theory no more (8) |
