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There are 17 clues with the answer 'TRANQUILLISER'
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CLUE
1.
Still lies about registered sedative (13)
2.
Ill in quarters (anag) - this should calm you (13)
3.
Writer in trainers popping pill
4.
A number observing old writer in new trainers
5.
Calming-down drug (13)
6.
Pill used to calm (13)
7.
Calming drug (13)
8.
Sedative (13)
9.
A calming drug (13)
10.
Calming drug
11.
Sedative
12.
Ill in quarters suffering, sedative needed (13)
13.
Medicinal drug taken to reduce anxiety (13)
14.
Sped with pen in further test after turning calmer (13)
15.
Calming narcotic (13)
16.
Medicinal drug taken to reduce tension or anxiety (13)
17.
Sedative or calming drug