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There are 21 clues with the answer 'SUGARSUBSTITUTE'
# CLUE
1.
Sweet freebie at a coffee bar
2.
Low-calorie sweetener
3.
Artificial sweetener ... and what the end of 17-, 26-, 48- and 58-Across is, literally
4.
Artificial sweetener in packets
5.
THEME OF THIS PUZZLE
6.
Sweetening agent
7.
Sweet'n low
8.
Sucralose
9.
Splenda, for example
10.
Splenda
11.
Sodium cyclamate
12.
Saccharin
13.
Pill in an envelope
14.
Nutrasweet
15.
EQUAL
16.
Cyclamates
17.
Common coffee flavorer
18.
Calcium cyclamate
19.
Aspartame
20.
Artificial sweetener
21.
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