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There are 12 clues with the answer 'SHREWDEST'
# CLUE
1.
The most sly and quiet drew apart, having no time for trial (9)
2.
Most intelligent rodent without hesitation in desert (9)
3.
Most canny (9)
4.
Least obtuse
5.
Most astute (9)
6.
Most cunning
7.
Most clever
8.
Most cagey
9.
Most astute
10.
Meanest
11.
Bitchiest
12.
Scold head of state entertained by Ted Turner? That's most astute (9)