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There are 8 clues with the answer 'SECONAL'
# CLUE
1.
Soporific plug screening scam
2.
Trade name for the sedative drug also called quinalbarbitone
3.
Sedative and hypnotic drug
4.
Brand-name calmer
5.
Can lose one with a barbiturate like this (7)
6.
It'll knock you out
7.
Eli Lilly sedative
8.
Commercial calmer