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There are 4 clues with the answer 'SAMANTHAWHO'
# CLUE
1.
2007-2009 ABC series where Jean Smart played Regina the mother of an amnesiac daughter: 2 wds.
2.
2007-2009 ABC sitcom starring Christina Applegate as a recovering amnesiac: 2 wds.
3.
2007-09 TV series with Melissa
4.
2000s sitcom about a woman with amnesia