Across and Down

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There are 10 clues with the answer 'ROADTORUIN'
# CLUE
1.
Alcohol or drugs, it's said
2.
Destructive path
3.
Way to Lindisfarne, say, is a downward spiral (4,2,4)
4.
Path heading for disaster (4,2,4)
5.
Path heading for disaster
6.
Disastrous path
7.
Ceaseless drinking or gambling, say
8.
Impending disaster
9.
Highway of overindulgence?
10.
Destructive habit, figuratively