Across and Down

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There are 20 clues with the answer 'RECTUM'
# CLUE
1.
Lowest section of the intestine (6)
2.
Last part of tract etc sadly dropping in spirit (6)
3.
Lowest section of the large intestine (6)
4.
Terminal section of the large intestine
5.
Last portion of intestine (6)
6.
Last portion of intestine
7.
Part of the large intestine
8.
End of a canal destroyed 'em, they say (6)
9.
Upright but not opening - I'm unsure it's part of the gut (6)
10.
Start to reconstruct stomach and part of the alimentary canal (6)
11.
Treatment for psychosis in strange part of the body! (6)
12.
Final section of large intestine
13.
Awkward customer so lost in passage (6)
14.
Part of the alimentary canal is so lacking in diseased customer (6)
15.
Desperate customers dispatch SOS a€“ it's close to the bottom (6)
16.
Something straight, upright, virtuous
17.
Strange to hold medical procedure where waste emerges (6)
18.
Reportedly cause damage to one part of the alimentary canal or another (6)
19.
Soundly damage corporation in the end
20.
Final section of the large intestine