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There are 9 clues with the answer 'ORIGINOFSPECIES'
# CLUE
1.
Classic of 1859, with "The"
2.
Influential work by 28-Across, familiarly
3.
Soporific 9 is encoded in 23's work (incomplete) (6,2,7)
4.
Theory of precision goes, if mutation occurs (6,2,7)
5.
Darwinian concern
6.
Darwin book title
7.
Darwin title subject
8.
Classic Charles Darwin work
9.
On the _ _ _ : 1859 scientific work that introduced the theory that populations evolve through natural selection (6,2,7)