Across and Down

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There are 19 clues with the answer 'OPIOID'
# CLUE
1.
Medication used for pain relief (6)
2.
Codeine's category
3.
Downer drug
4.
Oxy Contin, e.g.
5.
OxyContin, e.g.
6.
Fentanyl, e.g.
7.
Sedating substance
8.
Compound similar to morphine used for pain relief (6)
9.
Drug linked to a mid-2010s epidemic
10.
Subject of a U.S. drug epidemic
11.
Endorphin, for instance
12.
Narcotic (6)
13.
Strong pain reliever
14.
Sedative substance
15.
Narcotic
16.
Addictive substance stored in west-facing studio I possessed
17.
OxyContin, for example
18.
Drug class
19.
Dr. House's self-prescription