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There are 18 clues with the answer 'OPEROSE'
# CLUE
1.
Busy poet's request to flower to unfold?
2.
Industrious poet's exhortation to flower to unfold
3.
Not wholly uncorked wine, perhaps, is unusually like hard work (7)
4.
Uphill
5.
Strenuous
6.
Sticky
7.
Serious
8.
Rugged
9.
Persevering
10.
Laborious
11.
Labored
12.
Industrious
13.
Hardworking
14.
Hard
15.
Diligent
16.
Difficult
17.
Crucial
18.
Laborious exercises accepted by old woman