Across and Down

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There are 10 clues with the answer 'MICRODOSE'
# CLUE
1.
Go a little bit up or down?
2.
Drop just a drop?
3.
Take a small amount of a psychedelic
4.
Small amount of LSD, e.g.
5.
Very small amount of a drug
6.
Tiny amount of a hallucinogen
7.
Tiny amount of a psychedelic drug
8.
Take small amounts of a psychedelic drug
9.
Smallest effective amount of a substance
10.
Take small amounts of psychedelics