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There are 9 clues with the answer 'MANICDEPRESSION'
# CLUE
1.
It makes one mad, unhappily (5,10)
2.
Red spice mix in big house brings on mental instability (5,10)
3.
Disorder in persona medic's classified (5,10)
4.
"An Unquiet Mind" subject
5.
Psychotic
6.
Manicdepressive illness
7.
Clinical depression
8.
Bipolar disorder
9.
How bipolar disorder used to be known (5,10)