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There are 5 clues with the answer 'ISABELLAI'
# CLUE
1.
Catherine of Aragon's mum is a beautiful Italian (8,1)
2.
Queen of Castile who instituted the Spanish Inquisition with husband Ferdinand of Aragon (8,1)
3.
Queen of Castile 1474-1504 who, with her husband Ferdinand II, instituted the Spanish Inquisition and backed Columbus's expedition of 1492 (8,1)
4.
Catherine of Aragon's mom
5.
Intro removed from liberalisation amendment by Queen (8,1)