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There are 16 clues with the answer 'FLUSHOT'
# CLUE
1.
Pre-winter injection
2.
Winter protection?
3.
Annual health safeguard
4.
Doctor's fall offering
5.
Frequent subject in recent headlines
6.
Annual vaccination
7.
Annual inoculation
8.
Annual AMA recommendation
9.
Fall vaccination, for some
10.
Source of immunity
11.
Drugstore offering, perhaps
12.
Seasonal pharmacy offering
13.
Seasonal safeguard
14.
Annual injection for many
15.
Late autumn jab
16.
Annual health safeguard, for many