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There are 22 clues with the answer 'FERTILECRESCENT'
# CLUE
1.
Large region stretching from Armenia to Arabia, now mainly desert (7,8)
2.
An area of the Middle East good for growing crops (7,8)
3.
Boomerang-shaped region in the Middle East that nurtured early civilisations (7,8)
4.
"Cradle of Civilization"
5.
'Cradle of Civilization'
6.
Mainly desert area considered to be the cradle of civilisation (7,8)
7.
This name for an ancient and important area was apparently not used before the 20th century
8.
Middle East region often called "the cradle of civilization"
9.
*Cradle of civilization
10.
Ancient arc of civilisation from Iraq to Palestine (7,8)
11.
Ancient arc of civilisation running from Iraq to Palestine (7,8)
12.
Region from Armenia to Arabia considered to be the cradle of civilisation (7,8)
13.
Area that's mostly desert, despite its name
14.
Nicer trees left, possibly associated with onset of civilisation, here? (7,8)
15.
Cradle of early civilization
16.
Broad semicircle from the Nile to the Tigris and Euphrates
17.
Historical area in the Middle East
18.
Broad semicircle from the Nile to the Euphrates
19.
Home of the Sumerians
20.
Tigris-Euphrates region
21.
Area of early civilization
22.
Sickle-shaped region in the Middle East including modern-day Jordan and Iraq (7,8)