Across and Down

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There are 45 clues with the answer 'ESTRANGES'
# CLUE
1.
Alienates from friendship
2.
Loses affections with some sort of greatness (9)
3.
Alienates sergeants in mess (9)
4.
Drives away from eastern mountains, finding way through (9)
5.
How it alienates when anger sets out to disturb them (9)
6.
Unusual greatness causes alienation (9)
7.
Greatness anagram
8.
Greatness somehow causes alienation (9)
9.
Sets Regan at variance with friends! (9)
10.
Greatness somehow causes alienation
11.
Alienates (9)
12.
Greatness, unfortun-ately, makes enemies (9)
13.
Greatness, sadly, sets one apart (9)
14.
Alienates sergeants somehow (9)
15.
Withholds
16.
Withdraws
17.
Weans
18.
Turns away
19.
Turns
20.
Sunders
21.
Splits
22.
Severs
23.
Sets
24.
Separates
25.
Partes
26.
PARTS
27.
Opposes
28.
Makes
29.
Drives
30.
Divorces