Across and Down

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There are 5 clues with the answer 'EGODEATH'
# CLUE
1.
"Complete transcendence-beyond words, beyond space-time, beyond self," per "The Psychedelic Experience"
2.
Complete loss of self-identity
3.
Radical self-transformation after a drug trip, maybe
4.
Selfless act?
5.
Total loss of self-identity