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There are 17 clues with the answer 'BIGIF'
# CLUE
1.
Unlikely but necessary condition
2.
Major condition
3.
It's a lot to assume
4.
Huge uncertainty
5.
Fundamental question
6.
Hard-to-meet condition
7.
Significant qualification
8.
Major uncertainty
9.
Huge condition
10.
Problematic event
11.
"That's a ___!"
12.
"That's a ___!" ("You're making a huge assumption!")
13.
Hypothetical that's very unlikely to happen
14.
Hypothetical that's highly unlikely
15.
"That's a ___" ("That seems very unlikely")
16.
It's very unlikely to happen
17.
Major unsettled question