Across and Down

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There are 30 clues with the answer 'ANODYNES'
# CLUE
1.
Pain relief managed? Yes and no (8)
2.
Anyone suffering after swallowing some dubiously "special" painkillers? (8)
3.
Painkillers for nose Andy broke? (8)
4.
Bland, small painkillers (8)
5.
Pain-relieving medicines
6.
Unknown number in negative terminals - but they don't worry anyone (8)
7.
They relieve pain, but any dose must be regulated about the middle of the morning (8)
8.
A signal of approval-okay taking new painkillers (8)
9.
Send on a return about unknown pain-killers (8)
10.
Painkillers? Yes and no, surprisingly
11.
They relieve pain somehow? Yes and no
12.
Painkillers? Yes and no, unfortunately
13.
They avoid controversy? Yes and no, possibly (8)
14.
Soothing things
15.
Sedatives
16.
Painkillers
17.
Pain relievers
18.
Pain pills
19.
Narcotics
20.
Hypnotics
21.
Drugs
22.
Comforts
23.
Certain painkillers
24.
Balms
25.
Aspirin and codeine
26.
Anesthetics
27.
Analgesics
28.
Medicines that allay pain (8)
29.
After injury, no end say for pain killers (8)
30.
Pain-relieving medicines (8)