| GREATCIRCLE | Wonderful group of friends that takes the longest route round the world |
| MATURES | Group of friends that go round an ancient city reaches full development (7) |
| OLD | The kind of friends that go way back |
| OUTER | Circuitous route round the perimeter (5) |
| DOVERCASTLE | Led on tortuous route round dull old building near the cliffs (5,6) |
| BITER | Word for an onychophagist; an animal that nips or snaps; a fish that takes the bait; or, a curling stone that rests on the edge of the house (5) |
| VIOLETS | In exile on Elba, Napoleon told his friends that he would return to France with the appearance of what flowers in the spring? (7) |
| JOEY | 2004-6 spinoff of the US sitcom Friends that starred Matt LeBlanc and Andrea Anders (4) |
| PALS | Friends that surround the answers to 21-, 26-, 43- and 50- Across |
| FISHEATINGBIRDS | Feathered friends that might get their meals from the ocean |
| RACONTEUR | Storyteller overturned vehicle on new route round base of mountain |
| VISTA | This may be observed on the route round a street (5) |
| THESECRETRACE | Biography by Tyler Hamilton and Daniel Coyle that takes the readers to the professional world of cycling: 3 wds. |
| ABUTMENT | A construction that takes the thrust of an arch or vault or supports the end of a bridge |
| BOGGART | In the Harry Potter stories, a shapeshifter that takes the form of one's worst fear (7) |
| NOFRILLS | The bare bones of dressmaker's policy that takes the edge off (2-6) |
| NICK | Cut shot that takes the edge of the bat (4) |
| THEMUPPETS | Animal and friends that are felt up, among those friendly creatures? (3,7) |
| FLATMATES | Friends that sing off-pitch still share an apartment (9) |
| TRAVAIL | Hard work, making route round heart of Nevada |