| LITHOSPHERE | Wicked Hitler's hope to gain a region of the earth |
| BOOKMAKERS | They hope to gain from their betters (10) |
| LONGFOR | Hope to gain with some effort, at length? (4,3) |
| ASPIRE | Hope to gain |
| ZONA | A girdle, including of a region of the earth, vide Ov. Met. 1.46 |
| TROPIC | A region of the earth surrounding the Equator (6) |
| SIDE | Either of the two faces of a vinyl record; or, a region of the body between armpit and hip (4) |
| MANTLE | Region of the earth lying below the crust and above the central core (6) |
| TRACT | In anatomy, a region of the body containing a system of organs or tissues serving a particular function (5) |
| BELT | A region of the solar system beyond the orbit of Neptune, consisting of icy debris (6,4) |
| KUIPER | A region of the solar system beyond the orbit of Neptune, consisting of icy debris (6,4) |
| WINCH | To gain a companion, a cranky thing to do? (5) |
| STOWAWAY | A person who hides in a ship to gain a passage (8) |
| SYSTEM | A method by which a gambler hopes to gain an advantage over the house |
| IONOSPHERE | Region of the earth's atmosphere in which there is a high concentration of free electrons (10) |
| ARCTIC | Region of the Earth whose name means 'near the bear' |
| CORE | The central region of the earth (4) |
| OSSETS | Native or inhabitant of a region of the Caucasus Mountains which is divided by the boundary between |
| ANKLE | Known in Latin as the tarsus, a region of the body containing the talus and talocrural joint (5) |
| BLUEZONE | A term for a region of the world in which people tend to live longer (4,4) |