| LEWWALLACE | Author of 1880 novel Ben Hur (3,7) |
| HENRY | Author of 1880 novel Washington Square (5,5) |
| JAMES | Author of 1880 novel Washington Square (5,5) |
| WALLACE | Lew, author of the novel Ben-Hur (7) |
| NANA | Emile Zola novel of 1880 (4) |
| DMITRIKARAMAZOV | One of three title literary characters of 1880 |
| HUR | Ben-___ character from Lew Wallace's 1880 novel |
| BENHUR | 1880 novel by Lew Wallace subtitled A Tale of the Christ |
| HEIDI | Dete's niece, in a beloved 1880 novel |
| TRUMPETMAJOR | The ?, 1880 novel by Thomas Hardy (7-5) |
| BEN | 1880 novel by Lew Wallace featuring the character Messala (3-3) |
| DUKESCHILDREN | 'The --', 1880 novel by Anthony Trollope (5,8) |
| ENDYMION | 1880 novel by Benjamin Disraeli (8) |
| EUCALYPTUS | Tree of the myrtle family yielding timber, oil and gum; one of the biggest of such trees in Europe can be found in Galicia, Spain, called "El Abuelo" it was planted in around 1880, is nearly 70 metres |
| GADOLINIUM | Silvery-white metallic element of the lanthanide series discovered by Jean Charles de Marignac in 1880 (10) |
| JABOTINSKY | Russian Revisionist Zionist leader and co-founder with Trumpeldor of the Jewish Legion (1880-1940) (10) |
| SEANOCASEY | Irish dramatist, 1880-1964 (4,6) |
| TRUMPELDOR | Zionist activist who organized the Zion Mule Corps and helped bring Jewish immigrants to Palestine (1880-1920) (10) |
| SHOLEMASCH | Polish-Jewish novelist, dramatist, and essayist in Yiddish (1880-1957) (6,4) |
| PIERRE | State capital of South Dakota, founded in 1880 on the east bank of the Missouri River (6) |