| SCHIRRA | Astronaut Wally, who went into space in the Mercury, Gemini, and Apollo programs |
| HEAVYMETALTHUNDER | Uranium boom exploding into space in the Steppenwolf tune?: 3 wds. |
| ENOS | Chimp who went into space in 1961 |
| COLUMBIA | It went into space in newspaper feature, leaning characters on right missing (8) |
| JAKEGARN | Congressman who went into space |
| GARN | Senator from Utah who went into space |
| ALAN | Shepard who went into space |
| HELENSHARMAN | Chemist and astronaut who was the first British person to go into space, in 1991 (5,7) |
| CONSTANTINE | King of Greece who went into exile when the army seized power in 1967 (11) |
| SHENZHOU | Chinese space programme ('divine craft') whose fifth flight carried the first Chinese astronaut, Yang Liwei, into space in 2003 (8) |
| SHATNER | William, ex-Star Trek actor who became the oldest person to go into space in 2021 (7) |
| ALANSHEPARD | Test pilot who was the first American to travel into space, in 1961: 2 wds. |
| AMOS | Wally who played himself in the 'Taxi' episode 'Latka's Cookies' |
| WILLIAMSHATNER | Captain Kirk turned 90 and went into space, for real (7.7) |
| SNOWDEN | Man who went into self-imposed exile in 2013 |
| VOSTOK | ____ 1, the spacecraft that carried Soviet cosmonaut Yuri Gagarin into space in 1961 (6) |
| HAM | Famous chimp in the Mercury space program |
| KURTH | WALLY WHO IS GH'S NED AND DAYS'S JUSTIN |
| CASTOR | The stars in the constellation Gemini, ... & Pollux |
| THOMAS | Teenager who went into labour alone up at Home Farm recently (5,6) |
