| THEDANISHGIRL | *Film starring Eddie Redmayne as one of the first people to receive gender reassignment surgery |
| REDMAYNE | Actor who played the role of the first person to undergo gender reassignment surgery, Eddie. |
| DANISH | The _ Girl, 2016 film starring Eddie Redmayne (6) |
| FANTASTICBEASTS | Fantasy film series related to Harry Potter starring Eddie Redmayne as Newt Scamander (9,6) |
| THETHEORYOFEVERYTHING | 2014 biopic starring Eddie Redmayne as Stephen Hawking (3,6,2,10) |
| THETHEORYOF | 2014 biopic starring Eddie Redmayne as Stephen Hawking (3,6,2,10) |
| EVERYTHING | 2014 biopic starring Eddie Redmayne as Stephen Hawking (3,6,2,10) |
| SEXCHANGE | Small substitute for reassignment surgery (3,6) |
| MELLOW | Gentle chap having sex reassignment surgery |
| ROMAN | One of the first people to walk Watling Street? (5) |
| PREADAMITE | One of the first people (perhaps first) to study a parasite (3-7) |
| HUDSON | The Lenape and Algonquin were likely the first people to spot this English navigator heading north upriver from the Verrazano Narrows in 1609 (6) |
| LUTHERANS | Members of a denomination which included the first people to be called Protestants |
| ABEL | One of the first people in the Bible |
| EDITORS | The first people to try crosswords |
| PIONEERS | The first people to do something |
| RINGABELL | Recall one of the first people carried by Circle Line |
| SETH | One of the first people named in Somerset House (4) |
| CAIN | One of the first people entered, ignoring me |
| ENOS | One of the first people mentioned in Genesis |
